Site: The General Hospital Corporation At Mass General Brigham, we know it takes a surprising range of talented professionals to advance our mission—from doctors, nurses, business people and tech experts, to dedicated researchers and systems analysts. As a not-for-profit organization, Mass General Brigham is committed to supporting patient care, research, teaching, and service to the community. We place great value on being a diverse, equitable and inclusive organization as we aim to reflect the diversity of the patients we serve. At Mass General Brigham, we believe a diverse set of backgrounds and lived experiences makes us stronger by challenging our assumptions with new perspectives that can drive revolutionary discoveries in medical innovations in research and patient care. Therefore, we invite and welcome applicants from traditionally underrepresented groups in healthcare — people of color, people with disabilities, LGBTQ community, and/or gender expansive, first and second-generation immigrants, veterans, and people from different socioeconomic backgrounds – to apply. Job Purpose: The Manager, Biostatistics will be responsible for leading statistical operations, including overseeing implementation of design, analysis, validation, and reporting of data to support clinical research and investigational product development. The individual will ensure the application of rigorous, reproducible statistical methods and error-free statistical programming (SAS, R and/or other programming languages) to produce reliable and reproducible results. This individual will serve as a key biometrics advisor, will work closely with Healey Trial leadership, and will aid in the oversight of CROs, contractors, and interdisciplinary teams. Responsibilities Leadership and Project Oversight: Serve as the statistical operational team lead for the HEALEY ALS Platform Trial, overseeing the implementation of the design, execution, and reporting of each regimen. Statistical Analysis and Data Management: Utilize advanced programming skills (using SAS, R, or other statistical programming languages) to generate accurate and reproducible results. Operational and Financial Accountability: Develop project timelines, forecast resource needs, and identify and address potential out-of-scope work. Risk Management and Quality Assurance: Identify and proactively mitigate risks to project delivery and data quality. Collaboration and Communications: Act as a point of contact for MGH NCRI leadership, trial biostatisticians, and external stakeholders, consulting on statistical and operational topics. Qualifications PhD (or MS) in Biostatistics, Statistics, Computer Science, Mathematics, Engineering, Life Science or related field. 5+ years with a PhD, or 7+ years with MS focused on leading the conduct, data coordination, statistical analysis, and reporting of multisite phase I-III randomized trials in the Pharmaceutical & Biotech industry. Proficiency with SAS, R, or another statistical programming language. Advanced knowledge of biostatistics and its application to different phases of drug development in a regulatory environment. Exceptional attention to detail and organizational skills. Excellent written and verbal communication skills, with the ability to effectively collaborate with multidisciplinary teams. Job Summary: Responsible for the overall direction and functioning of the biostatistics program and its processes to ensure alignment with agency strategic goals. Does this position require Patient Care? No Additional Job Details: Hybrid work location, 40 scheduled weekly hours. EEO Statement: The General Hospital Corporation is an Affirmative Action Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. #J-18808-Ljbffr Mass General Brigham Health Plan, Inc.
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